The nuclear lamina consists of two components lamins and nuclear lamin associated membrane proteins. Evaluation of nuclear lamina proteins revealed lamin b1 cleavage that was prevented by caspase 6 casp6 inhibitor and exacerbated after pharmacologic genetic inhibition of trx1 system but not after glutathione depletion. Caspase 9 homologs have been identified in all mammals for which they are known to exist such as mus musculus and pan troglodytes.
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